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Research of endometrial receptivity and cavity environment in recurrent implantation failure patients in Beijing-Tianjin-Hebei region

Research of endometrial receptivity and cavity environment in recurrent implantation failure patients in Beijing-Tianjin-Hebei region

Status
Recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100054007
Enrollment
Unknown
Registered
2021-12-06
Start date
2022-01-01
Completion date
Unknown
Last updated
2022-11-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Recurrent implantation failure

Interventions

case series:none

Sponsors

Peking University People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Patients with a history of 3 embryo transfer failures, at least 4 high-quality embryos, and repeated implantation failures aged <40 years old; 2. Patients with BMI between 18.5-30 kg/m^2 who are planning to undergo thawed transplantation.

Exclusion criteria

Exclusion criteria: 1. History of recurrent miscarriage in the past, suffering from uterine submucosal fibroids; 2. Intramural fibroids larger than 4cm, adenomyosis, intrauterine adhesions, endometrial polyps, suffering from hydrosalpinx; 3. Endometrial <7mm before receiving the three-in-one test (EndomeTrio), allergic to antibiotics or unable to accept antibiotic treatment.

Design outcomes

Primary

MeasureTime frame
rate of live birth;

Secondary

MeasureTime frame
rate of clinical pregnancy;Characteristics of the composition of the intrauterine flora;rate of implantation ;rate of miscarriage;rate of ongoing pregnancy;

Countries

China

Contacts

Public ContactHan Hongjing

Peking University People's Hospital

han_hhj@126.com+86 13520161891

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026