Recurrent implantation failure
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with a history of 3 embryo transfer failures, at least 4 high-quality embryos, and repeated implantation failures aged <40 years old; 2. Patients with BMI between 18.5-30 kg/m^2 who are planning to undergo thawed transplantation.
Exclusion criteria
Exclusion criteria: 1. History of recurrent miscarriage in the past, suffering from uterine submucosal fibroids; 2. Intramural fibroids larger than 4cm, adenomyosis, intrauterine adhesions, endometrial polyps, suffering from hydrosalpinx; 3. Endometrial <7mm before receiving the three-in-one test (EndomeTrio), allergic to antibiotics or unable to accept antibiotic treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| rate of live birth; | — |
Secondary
| Measure | Time frame |
|---|---|
| rate of clinical pregnancy;Characteristics of the composition of the intrauterine flora;rate of implantation ;rate of miscarriage;rate of ongoing pregnancy; | — |
Countries
China
Contacts
Peking University People's Hospital