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Correlation between changes of pulmonary microbiota and expression of antibiotic resistance genes in patients with chronic obstructive pulmonary disease

Correlation between changes of pulmonary microbiota and expression of antibiotic resistance genes in patients with chronic obstructive pulmonary disease

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100053988
Enrollment
Unknown
Registered
2021-12-06
Start date
2022-07-01
Completion date
Unknown
Last updated
2022-11-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COPD

Interventions

No Antibiotic group:None

Sponsors

The University of Hong Kong-Shenzhen Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients with chronic obstructive pulmonary disease who meet the diagnostic criteria in the 2019 Global Strategy for Chronic Obstructive Pulmonary Disease (GLOD); 2. Patients admitted to hospital due to acute exacerbations requiring antibiotic treatment.

Exclusion criteria

Exclusion criteria: Combined respiratory virus, fungal, Mycobacterium tuberculosis, and non-tuberculous mycobacterial infections.

Design outcomes

Primary

MeasureTime frame
blood count;C reactive protein;Procalcitonin;

Countries

China

Contacts

Public ContactWang Hongxia

The University of Hong Kong-Shenzhen Hospital

wanghx5@hku-szh.org+86 13528460931

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026