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A prospective randomized controlled study using the ligamentum teres hepatis / great saphenous vein as a vascular substitute for hepatic outflow tract reconstruction in autotransplantation for end-stage hepatic alveolar echinococcosis

A prospective randomized controlled study using the ligamentum teres hepatis / great saphenous vein as a vascular substitute for hepatic outflow tract reconstruction in autotransplantation for end-stage hepatic alveolar echinococcosis

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100053983
Enrollment
Unknown
Registered
2021-12-05
Start date
2021-12-06
Completion date
Unknown
Last updated
2022-11-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatic alveolar echinococcosis

Interventions

Experimental group:Ligamentum teres hepatis was used intraoperatively
Control group:the great saphenous vein will be used to repair the defect hepatic outflow tract, and the same symptomatic treatment will be given after operation

Sponsors

The First Affiliated Hospital of Xinjiang Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
14 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Liver hydatid lesions invade the first, second or third hepatic hilum and cannot be radically removed by surgery; 2. The liver hydatid lesions invaded the retrohepatic inferior vena cava with a length of 1.5cm and a circumference of 120. ; 3. The liver volume on the healthy side reaches 40% of the standard liver volume or >800g; 4. Child-Pugh grade is A or C is downgraded to B after treatment; 5. Other measures such as surgical percutaneous transhepatic cholangiography and drainage (PTCD) or endoscopic nasobiliary drainage (ENBD) for moderate to severe jaundice reduce the jaundice to mild; 6. Extrahepatic distant metastases, such as lung and brain, are controlled by drug treatment or will not be life-threatening in the near future, or extrahepatic distant metastases (such as diaphragm, omentum, kidney) can be combined with resection.

Exclusion criteria

Exclusion criteria: 1. Diffuse disseminated lesions in the whole liver; 2. Combined with other measures such as surgical drainage of obstructive jaundice, the jaundice cannot be improved; 3. Combined with moderate to severe ascites, the ascites cannot be improved by clinical intervention; 4. Severe heart, brain, kidney, lung vital organ insufficiency and combined with other tumors, mental and psychological diseases; 5. Cystic hepatic hydatid disease.

Design outcomes

Primary

MeasureTime frame
Outflow tract stenosis;

Secondary

MeasureTime frame
Biliary leakage;bleeding;pulmonary infection;Postoperative hospital stay;

Countries

China

Contacts

Public ContactTuerganaili Aji

The First Affiliated Hospital of Xinjiang Medical University

tuergan78@sina.com+86 13699995676

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026