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Effects of early enteral nutrition on pancreatic fistula and long-term prognosis after distal pancreatectomy or partial pancreatectomy: a single-center randomized controlled study

Effects of early enteral nutrition on pancreatic fistula and long-term prognosis after distal pancreatectomy or partial pancreatectomy: a single-center randomized controlled study

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100053978
Enrollment
Unknown
Registered
2021-12-04
Start date
2021-12-07
Completion date
Unknown
Last updated
2023-07-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

the pancreatic neoplasm

Interventions

Experimental group:Start eating 3 days after the operation
Control group:Start eating 7 days after surgery

Sponsors

Peking University Third Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Patients who underwent open or laparoscopic resection of the body and tail of the pancreas or part of the pancreas between December 2021 and June 2023 (including those who underwent splenectomy of the body and tail of the pancreas); 2. The preoperative diagnosis is basically clear, and surgical treatment is feasible; 3. There is no absolute contraindication to surgery; 4. All patients or their families are informed about the risks and benefits of surgery, and sign the informed consent form for surgery.

Exclusion criteria

Exclusion criteria: 1. Those who have a history of cerebral infarction, a history of myocardial infarction, severe insufficiency of liver and kidney, and cardiopulmonary function in the past six months who cannot tolerate surgery; 2. Patients and their families have poor compliance and do not cooperate with treatment; 3. Except for combined gastrointestinal resection.

Design outcomes

Primary

MeasureTime frame
amylase level of drainage fluid;Postoperative pancreatic fistula;

Secondary

MeasureTime frame
peripancreatic effusion;pancreatic pseudocyst;postpancreatectomy hemorrhage;abdominal abscess;Disease-free survival;progression-free survival;Hospitalization cost;Length of postoperative hospital stay;

Countries

China

Contacts

Public ContactXiu Dianrong

Peking University Third Hospital

dianrong@163.com+86 15611908135

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 8, 2026