Post operative delirium
Conditions
Interventions
Experimental group1:Intermittent retrograde perfusion of the operative lateral cerebral perfusion according to cerebral oxygen monitoring values
Experimental group2:Contralateral retrograde perfusion according to ultrasound monitoring intermittently
Control Group:Selective cerebral perfusion according to clinical routine
Sponsors
Chengdu Third People's Hospital
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients aged >= 60 years who need total arch replacement surgery; 2. ASA III-IV patients; 3. The patient agrees, and the informed consent form must be signed by the patient or his family.
Exclusion criteria
Exclusion criteria: 1. Preoperative/previous history of neurological and psychiatric diseases; 2. Unable to accept cognitive assessment due to language, hearing and vision problems; 3. Severe carotid artery stenosis; 4. Severe liver and kidney dysfunction; 5. Associated with severe valve disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Daily Post-operative Delirium Occurrence;7-day Post-operative Delirium Occurrence; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cardiac Function Recovery Index;Post-operative Complications; | — |
Countries
China
Contacts
Public ContactXu Mingxing
Chengdu Third People's Hospital
Outcome results
None listed