Lumbar Degenerative Disc Disease
Conditions
Interventions
Experimental group:Oblique lumbar discectomy and fusion
Sponsors
Fujian Provincial Hospital
Eligibility
Sex/Gender
All
Age
45 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Middle-aged and elderly patients aged >= 45 years; 2. Repeated low back pain with radiating pain or numbness of the lower extremity nerve root; 3. The imaging manifestations of the intervertebral disc are L2,3, L3,4 or L4,5 single segment protrusion, prolapse or free type, and the protrusion is more than 6mm from the posterior edge of the vertebral body; 4. The target intervertebral disc on X-ray or MRI shows obvious signs of degeneration, including "black disc sign", intervertebral space collapse, intervertebral instability and Modic changes; 5. After 6 months of conservative treatment such as drugs and physical therapy, the symptoms are still repeated; 6. Patients voluntarily participate in clinical trials, sign informed consent, and cooperate with clinical follow-up.
Exclusion criteria
Exclusion criteria: 1. Severe spinal stenosis due to ligamentum flavum hypertrophy or bone hyperplasia, and imaging shows dorsal stenosis of the nerve root canal; 2. Abnormal hypertrophy of the psoas major muscle, vascular malformation, calcification of the intervertebral disc, too narrow or unclear structure between the anterior edge of the psoas major muscle and the abdominal aorta; 3. Combined with spinal tumor, infection, severe osteoporosis, the patient's overall physical condition is poor and cannot tolerate surgery; 4. History of previous abdominal surgery with incomplete follow-up data; 5. The investigator believes that other reasons are not suitable for participating in this clinical evaluation trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Japanese Orthopaedic Association Scores;Visual Analogue Scale;Oswestry disability index;Disc height;Foraminal height;Segmental lordosis;Cross-sectional area;Fusion rate;Short-Form 36 Health Survey;Complication; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incision length;Operation time;Intraoperative bleeding;Hospital stay; | — |
Countries
China
Contacts
Public ContactXu Jie
Fujian Provincial Hospital
Outcome results
None listed