chronic fatigue syndrome
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria for CFS subjects: 1. In line with the CFS diagnostic consensus (developed by the US CDC in 1994): (1) 1) Persistent or recurring fatigue, lasting more than 6 months; 2) Exclude various organic diseases that cause chronic fatigue according to the medical history, signs or laboratory test results. (2) and at least 4 of the following 8 items: 1) Short-term memory loss or inability to concentrate; 2) sore throat; 3) Lymph node pain; 4) Muscle soreness; 5) Joint pain without redness and swelling; 6) New headache; 7) Energy cannot be recovered after sleep; 8) Physical discomfort for 24 consecutive hours after physical or mental work. 2. Aged 20 to 65 years, gender is not limited; 3. Those who have not received other treatment plans that may affect the judgment of the results in the past 1 month; 4. Those who voluntarily participated in this study and signed the informed consent. Inclusion criteria for subjects without CFS: 1. Does not meet the CFS diagnostic consensus; 2. No mental illness; 3. Aged 20 to 65 years, gender is not limited; 4. Those who have not received other treatment plans that may affect the judgment of the results in the past 1 month; 5. Those who voluntarily participated in this study and signed the informed consent.
Exclusion criteria
Exclusion criteria: CFS subject exclusion criteria: 1. Fatigue symptoms can be relieved after rest; 2. Fatigue symptoms do not cause a substantial decline in work ability, educational ability, social activities, recreational activities and personal life ability; 3. Suffering from diseases that can clearly cause fatigue, such as tumors, diabetes, rheumatism and immune diseases; 4. Suffering from chronic diseases; 5. Patients with mental illness; 6. Pregnant and lactating women; 7. Those who have participated in other clinical trials or are participating in other clinical trials within 1 month; 8. Those who are not suitable for MRI examination, such as those with cardiac pacemakers, nerve stimulators, metal foreign bodies (metal implants, contraceptive rings), insulin pumps, etc. Exclusion criteria for subjects without CFS: 1. Suffering from chronic diseases; 2. Pregnant and lactating women; 3. Those who have participated in other clinical trials or are participating in other clinical trials within 1 month; 4. Those who are not suitable for MRI examination, such as those with pacemakers, nerve stimulators, metal foreign bodies (metal implants, contraceptive rings), insulin pumps, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Child Fatigue Scale;Joint movement angle; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life scale;Pittsburgh Sleep Quality Index;Brief profile of Mood States;Blood lactic acid;Blood cortisol;Blood immunoglobulin;C reactive protein;Tumor necrosis factor-a;gamma interferon;transforming growth factor-ß;Interleukin;Surface electromyography;Blood oxygen concentration;Joint moment;Isokinetic muscle strength test;Muscle condition rapid measurement system; | — |
Countries
China
Contacts
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine