nasopharyngeal carcinoma
Conditions
Interventions
Experimental group1:Delineation of tumor target volume before induction chemotherapy
Experimental group2:Delineation of tumor target area after induction chemotherapy
Sponsors
Affiliated Hospital of Southwest Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Histopathologically or cytologically diagnosed as nasopharyngeal carcinoma; 2. Voluntarily serve as the subject and sign the informed consent; 3. Patients aged 18 to 70 years; 4. Nasopharyngeal carcinoma patients with UICC7th stage II-IVb stage; 5. ECOG score is 0 to 2; 6. Self cells >= 4.0 x 10^9/L, neutrophils >= 2.0 x 10^9/L, platelets >= 1 00 x 10^9/L; 7. All indicators of liver function are within the range of 2 times the upper limit of normal, and the renal creatinine clearance rate is >= 60 ml/min; 8. Imaging examination confirmed no distant metastasis. 9. The patient is the first course of treatment.
Exclusion criteria
Exclusion criteria: 1. Pregnant and lactating women; 2. There are contraindications to radiotherapy and chemotherapy; 3. The treatment response cannot be clearly described; 4. Have received radiotherapy or chemotherapy; 5. Suffering from peripheral neurotoxicity of degree II or above, psychosis, congestive heart failure, angina pectoris, uncontrolled hypertension, myocardial infarction within 6 months, active infectious diseases, active peptic ulcer, uncontrolled diabetes and Medical complications such as taking high-dose hormones (20 mg prednisone or equivalent other hormones) in the past 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Short-term effect;survival rate;adverse reaction; | — |
Countries
China
Contacts
Public ContactXiang Li
Affiliated Hospital of Southwest Medical University
Outcome results
None listed