Insomnia Disorder
Conditions
Interventions
Insomnia Disorder:no
Sponsors
The People's Hospital of BiShan District, Chongqing
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Insomnia disorder group: 1. Right-handed; 2. Aged 18 to 60 years; 3. Primary school or above, those who know Chinese and understand the contents of the scale, who have completed the scale; 4. Willing to join the clinical trial, can cooperate with the subject research, and sign the informed consent; 5. Meet the diagnostic criteria for insomnia disorders in the American Diagnostic and Statistical Manual of Mental Disorders Fifth Edition (DSM-5); 6. Pittsburgh Sleep Quality Index (PSQI) >= 5 points; 7. In line with PSG performance of difficulty falling asleep/difficulty maintaining sleep/early awakening, AHI<5 times/hour. Healthy control group: 1. Right-handed; 2. Aged 18 to 60 years; 3. Primary school or above, those who know Chinese and understand the contents of the scale, who have completed the scale; 4. Willing to join the clinical trial, can cooperate with the subject research, and sign the informed consent; 5. Good sleep quality, good sleep habits, no sleep problems such as difficulty falling asleep, difficulty maintaining sleep or waking up early; 6. PSQI <= 4 points, SAS standard score<=50 points, SDS standard score <= 53 points; 7. PSG performance in line with the age-appropriate sleep structure and the proportion of sleep in each stage, AHI<5 times/hour.
Exclusion criteria
Exclusion criteria: 1. Past or current suffering from severe organic brain disease, severe heart, liver, kidney, lung and other physical diseases; 2. Those with contraindications to magnetic resonance imaging, such as implantation of vascular stents, pacemakers, metal dentures, hearing aids, etc., claustrophobia, etc.; or abnormal brain structure found by magnetic resonance imaging; 3. History of taking anti-anxiety, depression and sleep drugs in the past 2 weeks; 4. Past or current history of substance abuse or dependence; 5. Suffering from other serious mental illness or family history (such as schizophrenia, bipolar disorder, mental retardation, etc.); 6. Women who are pregnant or breastfeeding; or who are planning to become pregnant.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Diffusion Tensor Imaging;Patient Health Questionnaire;Generalized Anxiety Self-Rating Scale;Montgomery Depression Rating Scale;Insomnia Severity Scale;Epworth Sleepiness Scale;polysomnography;gene; | — |
Countries
China
Contacts
Public ContactYue Faguo
The People's Hospital of BiShan District, Chongqing
Outcome results
None listed