severe pneumonia
Conditions
Interventions
Experimental group:prone ventilation treatment
Control group:non-prone ventilation treatment
Sponsors
Zhongshan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for "severe pneumonia"; 2. Aged 18 to 85 years; 3. Gender is not limited; 4. Consciousness and ability of autonomous speech expression; 5. Patients who are receiving oxygen inhalation via nasal cannula, oxygen inhalation mask, high-flow nasal inhalation oxygen or non-invasive ventilator-assisted ventilation; 6.100mmHg < oxygenation index (PaO2/FiO2) < 250mmHg; 7. Voluntarily participate in this study and sign a written informed consent.
Exclusion criteria
Exclusion criteria: 1. There are contraindications to prone position ventilation, such as severe intra-abdominal hypertension, multiple trauma with unstable fractures, severe hemodynamic instability, and confirmed venous thromboembolism, and anticoagulation therapy is less than 2 days; 2. Pregnancy status; 3. Patients deemed unsuitable as research subjects by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 28-day mortality rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Rate of tracheal intubation;length of stay;Improvement rate of oxygenation index; | — |
Countries
China
Contacts
Public ContactChen Shujing
Zhongshan Hospital, Fudan University
Outcome results
None listed