Obesity, metabolic syndrome, non-alcoholic fatty liver disease
Conditions
Interventions
transient 
(FibroScan): 
(CAP) 
is 
used 
for 
quantitative 
diagnosis 
of 
steatosis
 
Sponsors
The First Affiliated Hospital of Jinan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients with body mass index (BMI) >= 40 kg/m2 and no combined medical problems and bariatric surgery will not bring excessive risks; 2. Patients with body mass index (BMI) >= 5 kg/m2 and with one or more severe obesity-related complications that can be corrected by bariatric surgery; 3. Patients whose body mass index (BMI) is 28-34.9 kg/m2, and despite having the best lifestyle and medications, type 2 diabetes and/or arterial hypertension and other metabolic syndromes are still poorly controlled; 4. Patients aged 18 to 65 years, with full understanding, agree to participate in this study; 5. Patients who agree to undergo routine intraoperative liver biopsy and have a valid pathological diagnosis.
Exclusion criteria
Exclusion criteria: 1. Patients who lose the ability of daily living; 2. Patients during pregnancy or breastfeeding; 3. Patients with severe liver and kidney insufficiency, cardiopulmonary insufficiency, or other serious diseases that have not received standard treatment before surgery; 4. Patients with severe mental illness in the past; 5. Patients in the active stage of tumors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Controlled attenuation parameter;Liver stiffness measurement;Non-alcoholic fatty liver disease pathology score; | — |
Countries
China
Contacts
Public ContactWang Cunchuan
The First Affiliated Hospital of Jinan University
Outcome results
None listed