colorectal cancer
Conditions
Interventions
Group 1:Standard chemotherapy + Quxie Capsule
Group 2:Maintenance treatment + Quxie Capsule
Group 3:Single drug chemotherapy or targeted therapy + Quxie Capsule
Group 4:Simple TCM treatment + Quxie Capsule
Sponsors
Xiyuan Hospital, China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged 18 years or above, gender is not limited; 2. Pathologically diagnosed as colorectal cancer; 3. The clinical stage is IV; 4. ECOG 0-2 points; 5. Expected survival period >= 3 months; 6. There are measurable lesions that meet the RECIST 1.1 criteria; 7. Voluntarily join the study and sign the informed consent; 8. Those who are expected to have good compliance can follow up the curative effect and adverse reactions according to the program requirements.
Exclusion criteria
Exclusion criteria: 1. Diarrhea > 3 times/day, or grade II and above diarrhea (CTCAE v4.03 classification); 2. Combined with severe cardiovascular system complications, cerebrovascular system complications, active hepatitis, severe liver and kidney dysfunction; 3. There are various factors that affect the absorption of oral drugs, such as inability to swallow and intestinal obstruction; 4. Any unstable situation or situations that may jeopardize the safety of patients and their compliance with the study, such as those with severe mental illnesses such as schizophrenia; 5. Patients who are about to or are participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Progression free survival;Disease control rate;Objective response rate; | — |
Countries
China
Contacts
Public ContactYang Yufei
Outcome results
None listed