Hypertension
Conditions
Interventions
Control group 1:Antihypertensive drugs
Experimental group 1:Antihypertension+biofeedback electrical stimulation
Control group 2:Antihypertension+anxiolytics
Experimental group 2:Antihypertension+anxiolytics+biofeedback electrical stimulation
Sponsors
Chinese PLA General Hosptial
Eligibility
Sex/Gender
All
Age
25 Years to 95 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for hypertension in ''Chinese Expert Consensus on the Diagnosis and Treatment of Hypertension (2014 Edition)'', the blood pressure continues to rise or the blood pressure is measured 3 times in a resting state on different days, and the systolic blood pressure is >=140 mm Hg (1mm Hg = 0.133 kPa) and/or diastolic blood pressure >= 90 mm Hg, or a diagnosed history of hypertension. 2.(1) Sleep disorders: The sleep quality of the patients was evaluated by the Insomnia Severity Index Scale, of which the total score of 8 points and above was considered to have sleep disorders; (2) Anxiety state: GAD-7 scale was used to evaluate the patient's psychological state, of which there was anxiety state with a total score of 9 or more; (3) Depressive state and somatic symptoms: The PHQ-9 scale was used to evaluate whether the patients had depression, and those with a total score of 9 or more were defined as having a depressive state; The PHQ-15 scale was used to evaluate whether the patients had physical problems, and those with a total score of 9 or more were defined as having physical symptoms.
Exclusion criteria
Exclusion criteria: 1. Secondary hypertension; 2. In the acute phase of the disease, hemodynamic instability, such as rapidly progressive hypertension, acute myocardial infarction, acute heart failure, acute pancreatitis, etc.; 3. Poor control of chronic obstructive pulmonary disease (respiratory failure state); 4. Patients with renal insufficiency (CKD stage 4); 5. Patients with hepatic insufficiency; 6. Patients with diabetic ketoacidosis; 7. Patients with type 1 diabetes; 8. Patients with advanced malignant tumor (survival period < 1 year); 9. Suffering from skin diseases or allergies, unable to contact materials such as patches for a long time; 10. Suffering from mental disorders (diagnosed by psychiatry specialists); 11. Pregnant patients; 12. Any poorly controlled systemic disease; 13. The patient refused to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24-hour ambulatory blood pressure;blood pressure variability; | — |
Countries
China
Contacts
Public ContactXu Yong
Outcome results
None listed