Distant metastasis of breast cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 18-70 years, pathological diagnosis can be obtained by surgery or biopsy. 2. Clinically diagnosed or diagnosed breast cancer. 3. Biopsy has confirmed tumor in some organs. 4. An informed consent form must be signed in writing by the subject or his legal guardian or caregiver. 5. If necessary, the subject may be accompanied by a caregiver. 6. Subjects or their legal representatives understand and sign written informed consent prior to any evaluation. 7. Female subjects must have medical records to prove that they have been sterilized by surgery (such as hysterectomy, bilateral oophorectomy or tubal ligation) or menopause for more than one year; if there is still the ability to conceive, isolation contraceptive measures must be taken during this study period. 8. Willingness and ability to cooperate with all projects of this research.
Exclusion criteria
Exclusion criteria: 1. Suffering from gastrointestinal, cardiovascular, renal, blood system, endocrine, respiratory system, immunodeficiency or other serious diseases. 2. In the past year, due to other clinical medical or scientific research needs, received ionizing radiation outside the scope of this experiment, so that the annual radiation exposure dose exceeded 50 mSv. 3. History of drug or alcohol abuse. 4. Pregnant or lactating patients. 5. The venous condition is poor and cannot tolerate repeated venipuncture. 6. Received experimental drug or device treatment (with unclear effect or safety) within 1 month. 7. May be allergic to the components of 99mTc-Dar2 injection. 8. Have any conditions that the host of this study believes that any link related to this experiment may cause harm or have potential harm.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of the correlation between 99mTc-Dar2 uptake and integrin a6 expression levels in tumor tissues; | — |
Countries
China
Contacts
Sun Yat-sen Memorial Hospital of Sun Yat-sen University