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Clinical observation of different doses of Butorphanol tartrate combined with ketorolac ambutritol for postoperative analgesia in patients undergoing thoracoscopic surgery

Clinical observation of different doses of Butorphanol tartrate combined with ketorolac ambutritol for postoperative analgesia in patients undergoing thoracoscopic surgery

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100053775
Enrollment
Unknown
Registered
2021-11-29
Start date
2021-12-01
Completion date
Unknown
Last updated
2022-10-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thoracoscopic lobectomy

Interventions

Control group:Sufentanil combined with ketorolac ambutritol
Experimental group1:Low dose of butorphanol tartrate combined with ketorolol tritriol
Experimental group2:Medium dose of butorphanol tartrate combined with ketorolol tritriol
Experimental group3:High dose of butorphanol tartrate combined with ketorolol tritriol

Sponsors

The First Affiliated Hospital of DaLian Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 65 years, gender is not limited; 2. Patients who received conventional thoracoscopic radical resection of lung cancer; 3. ASA classification I or II; 4. 18kg/m^2 < BMI < 30kg/m^2; 5. Clearly understand and voluntarily participate in the research, and sign the informed consent form by myself.

Exclusion criteria

Exclusion criteria: 1. Long-term history of taking sedative and analgesic drugs; 2. Have a history of gastrointestinal ulcers and blood system diseases; 3. Liver, kidney and coagulation dysfunction; 4. Intelligence, language disorder, schizophrenia, severe depression.

Design outcomes

Primary

MeasureTime frame
Visual Analogue Scale Score;

Secondary

MeasureTime frame
untoward effect;40-item Recovery Quality Scale Score;Ramsay sedation score;Changes of Th17/Treg levels at different time points in peripheral blood;

Countries

China

Contacts

Public ContactWen Qingping

The First Affiliated Hospital of Dalian Medical University

abc1010961204@qq.com+86 18098877988

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026