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Prognostic Value of Coronary Microvascular Dysfunction Derived by Coronary Angiography derived Index of Microvascular Resistance in Patients with Myocardial Infarction with Non-Obstructive Coronary Arteries: A Prospective Multicenter Cohort Study

Prognostic Value of Coronary Microvascular Dysfunction Derived by Coronary Angiography derived Index of Microvascular Resistance in Patients with Myocardial Infarction with Non-Obstructive Coronary Arteries: A Prospective Multicenter Cohort Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100053771
Enrollment
Unknown
Registered
2021-11-29
Start date
2021-12-01
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myocardial Infarction with Non-Obstructive Coronary Arteries

Interventions

Case series:None

Sponsors

Shanghai Tenth People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged > 18 years 2. Meet the diagnostic criteria of MINOCA, that is, meet the diagnostic criteria of AMI (troponin elevation exceeds the upper limit of 99%, and is accompanied by at least one of the following: (1) symptoms of acute myocardial ischemia; (2) New ischemic ECG changes; (3) Pathological Q wave; (4) Imaging shows the loss of viable myocardium or new segmental weakening of ventricular wall motion; (5) Coronary thrombus confirmed by intraluminal imaging or autopsy such as CAG; no significant coronary stenosis (including normal and <50% stenosis); excluding other clinical diseases that cause AMI, such as myocarditis and pulmonary embolism. 3. Be able to understand the research purpose, voluntarily participate in the research and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. 3-5 myocardial infarction; 2. Have received thrombolytic therapy before CAG; 3. Severe liver and kidney disease; 4. Combined with a history of malignant tumor, life expectancy is less than 1 year; 5. Pregnant women or women planning to become pregnant in the near future; 6. The subjects have participated in or are participating in clinical trials of any other device or drug within the past 3 months; 7. The investigator believes that the subject has other circumstances that are not suitable for clinical trials.

Design outcomes

Primary

MeasureTime frame
Major adverse cardiac events;

Countries

China

Contacts

Public ContactChe Wenliang

Tenth People's Hospital Affiliated to Tongji University

chewenliang@tongji.edu.cn+86 86 21 66307259

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026