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Comparative study of cyclopofol and propofol in general anesthesia induction in children's elective surgery

Comparative study of cyclopofol and propofol in general anesthesia induction in children's elective surgery

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100053767
Enrollment
Unknown
Registered
2021-11-29
Start date
2021-11-29
Completion date
Unknown
Last updated
2022-10-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia

Interventions

Experimental group1:Use propofol 2.5 mg/kg for induction
Experimental group2:Use Ciprofol 0.5 mg/kg for induction
Experimental group3:Use Ciprofol 0.6 mg/kg for induction

Sponsors

Plastic Surgery Hospital of Chinese Academy of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 12 Years

Inclusion criteria

Inclusion criteria: 1. Elective surgery requiring endotracheal intubation; 2. Aged 6 to 12 years, gender is not limited; 3. ASA classification I or II; 4. BMI < 30kg/m2.

Exclusion criteria

Exclusion criteria: 1. Those with contraindications to general anesthesia or those who have had a history of anesthesia accident in the past; 2. Known or suspected allergies or contraindications to propofol injection, cyclopofol injection excipients, benzodiazepines, opioids, muscle relaxants, etc.; 3. Patients with cardiovascular, respiratory, nervous and endocrine system diseases; 4. Patients with abnormal liver and kidney function; 5. The subject cannot cooperate and needs to be induced by inhalation; 6. Subjects who are considered by the investigator to have any other factors that are not suitable for participating in this trial.

Design outcomes

Primary

MeasureTime frame
Anesthesia induction success rate;

Secondary

MeasureTime frame
Time to the disappearance of eyelash reflex;Change of electroencephalogram Bispectral Index during induction;Changes in blood pressure during induction;Incidence of injection pain;

Countries

China

Contacts

Public ContactJin Zibin

Plastic Surgery Hospital of Chinese Academy of Medical Sciences

jinzibin1990@163.com+86 18813019515

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026