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Evaluating the risk factors of postoperative nausea and vomiting for patients with breast cancer: analyzing the influence of GDF-15 and the therapeutic effect of transcuataneous electrical stimulation of acupoints

Evaluating the risk factors of postoperative nausea and vomiting for patients with breast cancer: analyzing the influence of GDF-15 and the therapeutic effect of transcuataneous electrical stimulation of acupoints

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100053752
Enrollment
Unknown
Registered
2021-11-28
Start date
2021-11-22
Completion date
Unknown
Last updated
2022-10-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

breast cancer

Interventions

Experimental group1(SNVP group):SNVP + traditional prophylactic treatment group
Experimental group2 (MNVP group):traditional prophylactic treatmentgroup
Experimental group3 (SNVP group):combined prophylactic treatment
Experimental group4 (MNVP group):combined prophylactic treatment

Sponsors

Chinese Academy of Medical Sciences Cancer Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Patients who have given birth to at least one child in a full-term pregnancy; 2. Aged 18 to 60 years; 3. Histologically or cytologically confirmed breast adenocarcinoma; 4. American society of anesthesiologists (American society of anesthesiologists, ASA) grade I or II.

Exclusion criteria

Exclusion criteria: 1. Suffering from Meniere motion sickness; 2. Diabetic patients; 3. Have used antiemetic drugs within 24 hours or received surgical treatment within 30 days; 4. Pregnant or lactating women; 5. Long-term drinking, long-term use of psychotropic drugs such as sedatives or antidepressants; 6. Patients with digestive system diseases such as gastric ulcer or liver and kidney diseases; 7. Allergy to anesthetics; 8. Preoperative radiotherapy or chemotherapy; 9. Unable to cooperate with the research for any reason, such as the following: language comprehension difficulties, mental illness, etc.

Design outcomes

Primary

MeasureTime frame
growth differentiation factor-15;

Secondary

MeasureTime frame
Postoperative nausea and vomiting;

Countries

China

Contacts

Public ContactWang Baona

Chinese Academy of Medical Sciences Cancer Hospital

wangbaona1987@163.com+86 18612115010

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026