novel coronavirus pneumonia
Conditions
Interventions
Case series:Bacillus subtilis spore
Sponsors
DreamTec Limited
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. healthy; 2. age over 25 years; 3. the outcome of the following examinations should be clinically insignificant: medical and surgical history (hypo-, hypertension, allergy, other diseases, major surgery, micturition, defecation, sleep, illness within the last 4 weeks prior to the start of the trial); 4. participant vaccinated with Sinovac over 4 months; 5. anti-SARS CoV 2 neutralizing antibody is negative in serum.
Exclusion criteria
Exclusion criteria: 1. pregnant women; 2. history of COVID-19 infection or showing COVID-19 infection symptoms; 3. having had contact to people with known COVID-19 infection in the last 14 days; 4. having fever (> 37.4oC in the last 24 hours), dry cough or feeling tired and having aches and pains, nasal congestion, runny nose, sore throat and diarrhea; 5. positive real time RT-PCR COVID-19 test; 6. persons with autoimmune diseases; 7. allergic diathesis or any clinically significant allergic disease (i.e. asthma); 8. any condition that might impair the immune response; 9. recent or current immunosuppressive medication; 10. any other vaccine application 30 days before the first dose.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Weight; | — |
Secondary
| Measure | Time frame |
|---|---|
| Neutralizing antibody level; | — |
Countries
China
Contacts
Public ContactKwong Wai Yeung
Dreamtec Limited
Outcome results
None listed