weaning
Conditions
Interventions
experimental group:Dual-mode weaning
control group:conventional weaning
Sponsors
The First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. At least 48 hours of invasive mechanical ventilation; 2. The SBT test failed after tracheotomy, and it is expected that the machine cannot be weaned in the short term; 3. Aged 18 to 85 years; 4. Clear consciousness, Glasgow score >= 13; 5. Have the ability to breathe spontaneously; 6. PaO2/FiO2 > 150; 7. No upper airway obstruction.
Exclusion criteria
Exclusion criteria: 1. Facial or skull trauma or surgery; 2. Facial abnormalities; 3. Recent gastric or esophageal surgery; 4. Upper gastrointestinal bleeding; 5. Pneumothorax patients; 6. Lack of cooperation; 7. Those with contraindications to non-invasive mechanical ventilation; 8. End-stage patients; 9. Patients who have been included in other trials; 10. Patients who refused to participate in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of mechanical ventilation after randomization; | — |
Secondary
| Measure | Time frame |
|---|---|
| total duration of mechanical ventilation;Success rate of weaning;length of stay in hospital;hospital mortality rate ;Ventilator associated complications;diaphragmatic muscle function;90-day survival rate; | — |
Countries
China
Contacts
Public ContactGuo Shuliang
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed