Residual symptoms of depression
Conditions
Interventions
Experimental group:Exercise and drugs
Sponsors
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 55 years; 2. In the past 18 months, patients diagnosed with depression in the outpatient clinic (according to the DSM-V diagnostic criteria for depression) have received drug treatment for at least 8-12 weeks, of which the treatment has been discontinued for no more than 2 weeks; 3. Hamilton Depression Scale = 50%, PHQ-15 >= 5 points; 4. Exercise habits - sit still, less than 60 minutes of aerobic exercise per week; 5. The native language is Chinese, and the informed consent is signed.
Exclusion criteria
Exclusion criteria: 1. Mental disorders including schizophrenia, bipolar disorder, suicidal major depression, alcoholism or other substance abuse; 2. Nervous system diseases, cardiovascular diseases, lung diseases, endocrine system and other diseases that cannot be exercised; 3. Has participated in another clinical trial related to exercise or weight management or a family member has participated in this experiment; 4. Taking drugs that affect heart rate and blood pressure; 5. Physical conditions that are not suitable for exercise, such as asthma, arthritis, gout, rheumatoid, back and knee pain, cancer, Crohn's disease, etc.; 6. Cannot exercise continuously for 30 minutes; 7. Patients with contraindications to taking antidepressants; 8. Serious impairment of visual, auditory and cognitive functions, and eye diseases; 9. BMI greater than 35 or less than 18; 10. Breastfeeding, pregnant, or planning to become pregnant during the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Residual symptoms of depression remission rate; | — |
Countries
China
Contacts
Public ContactYang Yuan
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed