acute acquired concomitant esotropia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: AACE group: (1) Aged >= 5 years; (2) Meet the diagnostic criteria for acute acquired concomitant esotropia (3) Best corrected visual acuity in both eyes>=1.0; (4) Be able to understand and cooperate with the inspection, and voluntarily sign the informed consent form. Control group: (1) Aged >= 5 years; (2) The best corrected visual acuity of both eyes >=1.0; (3) The eye position is upright and the binocular vision function is normal; (4) Be able to understand and cooperate with the inspection, and voluntarily sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Suffering from organic eye disease; (2) Past history of eye surgery; (3) Accompanied by vertical strabismus; (4) Have a history of central nervous system; (5) Contraindications for magnetic resonance examination, including: metal orthodontics, cardiac pacemakers, artificial prostheses or joints claustrophobia, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| treatment success rate after 1, 3, 6 months of treatment;Innervation detection;Detection of the expression level of muscle-derived neurotrophic factor; | — |
Secondary
| Measure | Time frame |
|---|---|
| binocular vision function;ocular accommodation, convergence;EOM MRI;BOLD-fMRI;diplopia questionnaire score;ASQE score;complications;identification of amblyopia and strabismus;Optometry examination;best corrected visual acuity;retinal photography; | — |
Countries
China
Contacts
Beijing Tongren Hospital