Study on the effect of preoperative oral branched chain amino acids on postoperative insulin resistance in patients with colorectal cancer

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100053715

Enrollment

Unknown

Registered

2021-11-28

Start date

2021-12-01

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer

Interventions

Control group:Drink pure water before surgery

Experimental group1:Drink low-dose BCAA before surgery

Experimental group2:Drink high-dose BCAA before surgery

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 18 to 80 years; 2. Colorectal malignant tumor confirmed by pathology before surgery; 3. In the perioperative period, a modified enhanced recovery diagnosis and treatment program was adopted.

Exclusion criteria

Exclusion criteria: 1. Diabetes; 2. Preoperative insulin resistance; 3. Dialysis is required for renal insufficiency, and hepatic insufficiency (Child-Pugh grade B or above); 4. Eating disorders caused by gastrointestinal obstruction; 5. Distant metastasis of tumor.

Design outcomes

Primary

Measure	Time frame
Postoperative blood glucose level;	—

Secondary

Measure	Time frame
Fast insulin level in the first postoperative day;Hospital stay;Postoperative complications;	—

Countries

China

Contacts

Public ContactSun Peng

Shanghai Tongren Hospital

sp2082@shtrhospital.com+86 13916609133

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026