Cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 40 to 75 years (including critical value), gender is not limited; 2. Physical examination in the research center and no history of tumor; 3. Subjects who can voluntarily complete the "Population Health Tracking Survey - Simplified Questionnaire" according to the design of this research program and receive annual follow-up physical examination; 4. Agree to timely feed back the information related to tumor diagnosis in the process of visiting a doctor in a foreign hospital to the researcher during the research process; 5. Those who have no family planning in the past 3 years; 6. Those who have a full understanding of this research and voluntarily sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Those who have been diagnosed with esophageal cancer, gastric cancer, colorectal cancer, liver cancer, lung cancer, pancreatic cancer, breast cancer (including non-primary, such as recurrence, metastasis or other complications) and other malignant tumors; 2. Those who have received major surgery such as blood transfusion and transplantation within 3 months; 3. Participate in other interventional clinical investigators within 3 months; 4. Pregnant or lactating women; 5. Those who suffer from autoimmune diseases, genetic diseases, mental diseases/disability and other diseases that the researchers consider unsuitable to participate in this study; 6. The compliance is poor, and it is judged by the researcher that the researcher cannot be completed.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ctDNA methylation;ctDNA mutation;cfDNA fragmentation;sensitivity, specificity, positive predictive value and negative predictive value; | — |
Countries
China
Contacts
Fudan University Taizhou Institute of Health Sciences