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Ready-to-eat probiotics freeze-dried powder (Lactobacillus rhamnosus LRa05) Intervention to improve acute watery diarrhea in children

To evaluate the clinical efficacy and safety of Lactobacillus rhamnosus LRa05 in improving acute watery diarrhea in children

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100053700
Enrollment
Unknown
Registered
2021-11-27
Start date
2021-12-30
Completion date
Unknown
Last updated
2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dysentery

Interventions

intervention group:Conventional treatment +Take ready-to-eat probiotic freeze-dried powder Lactobacillus rhamnosus LRa05
Control group:Conventional treatment

Sponsors

Chengdu Women and Children's Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 3 Years

Inclusion criteria

Inclusion criteria: (1) Age: children (0-3 years old). (2) The duration of diarrhea was more than 12 hours but less than 72 hours; (3) non-bacterial infectious diarrhea; (4) Written informed consent was obtained from the supervisors of the enrolled children.

Exclusion criteria

Exclusion criteria: (1) chronic and persistent diarrhea; (2) outlet obstruction caused by congenital intestinal malformation and difficult defecation; (3) Neurodevelopmental disorders and severe organic diseases, Severe malnutrition, immunodeficiency diseases, pancreatic dysfunction, Bloody purulent stools, short bowel syndrome, bile or bloody vomit; (4) secondary diarrhea; (5) patients with moderate or severe dehydration or severe condition requiring PICU treatment; (6) taking probiotics before or within one month of the diagnosis; (7) Expected use of antibiotics during the trial; (8) The child was diagnosed with allergic diarrhea.

Design outcomes

Primary

MeasureTime frame
Number of diarrhea;stool property;

Countries

China

Contacts

Public ContactChen Ke

Chengdu Women and Children's Central Hospital

263662086@qq.com+86 139 8178 2973

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 5, 2026