Functional constipation
Conditions
Interventions
Experimental group:take evaluate whether daily administration of bifidobacterium lactis XLTG11
Control group:Oral lignolose solution (0.667g lignolose per 1ml) was given 5ml/ time, once a day, taken orally in the morning, for 14 consecutive days
Sponsors
Chengdu Women and Children's Central Hospital
Eligibility
Sex/Gender
All
Age
No minimum to 3 Years
Inclusion criteria
Inclusion criteria: 1. Rome IV diagnostic criteria at least two of the following symptoms persist for at least 1 month and the following symptoms cannot be explained by another disease: two or less bowel movements per week; history of stool retention; painful or hard bowel movements History of stool; history of bowel movements; large fecal mass in the rectum. At the same time, organic diseases can be excluded before the diagnosis of functional constipation in infants and young children; 2. Term infants, that is, gestational age from 37 to 42 weeks; 3. Birth weight between 2500–4000g; 4. Enrollment age: 6 months to 3 years old; 5. Parents voluntarily defer major changes in infant feeding practices; 6. Parents are willing and able to fill in diaries and questionnaires; 7. Written signed parental informed consent; 8. Periodic and effective visits can be made during the trial period.
Exclusion criteria
Exclusion criteria: 1. Chronic diseases or major medical problems; 2. Gastrointestinal organic diseases; 3. Growth retardation; 4. The mother or child of the breastfeeding child used antibiotics within 2 weeks before randomization and during the trial; 5. Infants (in formula and/or supplements) or their mothers used probiotics within 2 weeks before randomization and during the trial; 6. Has participated in other clinical trials; 7. Food allergies cause constipation (such as milk, eggs and other foods).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Defecate frequency;Fecal character;Difficulty in defecating; | — |
Countries
China
Contacts
Public ContactChen Ke
Chengdu Women and Children's Central Hospital
Outcome results
None listed