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Clinical efficacy of combining Huaiqihuang Granules with ARB in the treatment of chronic glomerulonephritis (Qi and Yin deficiency type)-a prospective randomized controlled study

Clinical efficacy of combining Huaiqihuang Granules with ARB in the treatment of chronic glomerulonephritis (Qi and Yin deficiency type)-a prospective randomized controlled study

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100053690
Enrollment
Unknown
Registered
2021-11-27
Start date
2021-11-29
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic glomerulonephritis

Interventions

Test group:Valsartan Tablets combined with Huaiqihuang Granules

Sponsors

the First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria of western medicine for chronic glomerulonephritis, and 24-hour urine protein quantitative = 60mL/(min/1.73m^2); 2. In line with TCM syndrome differentiation of Qi and Yin deficiency; 3. Aged 18-70 years, gender is not limited.

Exclusion criteria

Exclusion criteria: 1. Patients treated with glucocorticoids or other immunosuppressants; or patients who have discontinued hormones and immunosuppressants for less than 1 year; 2. Diabetic patients; 3. Pregnant or lactating patients; 4. Accompanied by serious other systemic diseases such as abnormal heart function, lung function, liver function, bone marrow hematopoietic disorder, etc.; 5. Patients with chronic gastritis or active gastric ulcer should not take Huaiqihuang Granules; 6. Patients with mental illness and cognitive dysfunction who cannot cooperate with the treatment; 7. Patients with allergic reactions to Huaiqihuang Granules.

Design outcomes

Primary

MeasureTime frame
24-hour urine protein quantification;TCM syndrome integral;

Countries

China

Contacts

Public ContactZhao Xi

The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine

zhaoxi614@163.com+86 18602212768

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026