Correlation between intracranial arterial vessel wall enhancement (IAVWE) and downstream cerebral blood perfusion

Correlation between intracranial arterial vessel wall enhancement(IAVWE) and downstream cerebral blood perfusion

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100053661

Enrollment

Unknown

Registered

2021-11-26

Start date

2021-12-01

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischaemic cerebrovascular disease

Interventions

Group according to local stenosis rate of lesions:Nil

Group according to whether there is arterial vessel wall enhancement:Nil

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Arteriosclerotic patients with unilateral middle cerebral artery M1 stenosis (stenosis rate greater than 20%) accompanied by stroke or transient ischemic attack; 2. No cerebral hemorrhage, brain tumor; 3. No history of thrombolysis, endovascular treatment and other special treatment.

Exclusion criteria

Exclusion criteria: 1. Associated with multiple stenosis of the middle cerebral artery; 2. Poor quality of magnetic resonance images affects measurement and evaluation; 3. Associated with intracranial or extracranial aneurysm, arterial dissection; 4. MRI contraindications; 5. Accompanied by myocardial infarction, cardiac insufficiency, abnormal liver function and renal function.

Design outcomes

Primary

Measure	Time frame
early arrival blood flow ratio;late arrival reverse blood flow ratio;Hypoperfusion intensity ratio;National Institute of Health Stroke Scale;	—

Countries

China

Contacts

Public ContactYan Liqun

The Second Hospital of Hebei Medical University

274934681@qq.com+86 15803218338

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 8, 2026