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To establish the clinical intervention study of 'precision medication'mode of meropenem in neurosurgery patients

To construct a complete closed-loop management model of meropenem 'precision drug use' in neurosurgery patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100053649
Enrollment
Unknown
Registered
2021-11-26
Start date
2021-12-01
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe infection

Interventions

Closed-loop management group:Construction of a closed-loop clinical application management system for meropenem
Non-closed loop management group:None

Sponsors

Suzhou Municipal Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Neurosurgery patients with pulmonary infection and central nervous system infection; 2.Empirical or targeted use of meropenem for anti-infective treatment.

Exclusion criteria

Exclusion criteria: 1.Meropenem medication is less than 3 days; 2.The timing of meropenem valley concentration sampling is unreasonable; 3.Meropenem allergic reaction occurs; 4.Patients undergoing renal replacement therapy and hemodialysis; 5.Patients with incomplete clinical evaluation data.

Design outcomes

Primary

MeasureTime frame
Basic Information;Medication Information;Blood trough concentration and cerebrospinal fluid concentration information;Curative effect evaluation index;Indicators related to adverse reactions;—

Countries

China

Contacts

Public ContactTang Lian

Suzhou Municipal Hospital

tanglian716@aliyun.com+86 15250491039

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026