Cardiac and electroencephalogram association study of etomidate reduction in elderly frailty patients

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100053639

Enrollment

Unknown

Registered

2021-11-26

Start date

2021-12-01

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

General anesthesia for elderly patients with frailty

Interventions

Frailty group:Etomidate pump injection

Non-frailty group:Etomidate pump injection

Eligibility

Sex/Gender

All

Age

65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Patients under general anesthesia for elective non-cranial or cardiac surgery; 2.Aged more than 65 years, gender unlimited; 3.BMI 18-30 kg/m^2; 4.Normal communication; 5.Voluntary subjects signed informed consent were selected.

Exclusion criteria

Exclusion criteria: 1.Patients who are taking any form of analgesic or neuromodulation drugs; 2.Dementia, mental retardation or other neuropsychiatric diseases; 3.People with hearing disabilities; 4.Patients with cerebrovascular history; 5.Other factors lead to communication difficulties in patients.

Design outcomes

Primary

Measure	Time frame
Etomidate dosage;	—

Secondary

Measure	Time frame
Electroencephalogram;Hemodynamic change;Use of vasoactive drugs;Heart rate;	—

Countries

China

Contacts

Public ContactChen Lijian

The First Affiliated Hospital of Anhui Medical University

chenlijian77@126.com+86 13966999467

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026