Predictive value of serum cystatin-C combined with urinary neutrophil gelatinase-associated lipid carrier protein in elderly patients with acute kidney injury after major orthopedic surgery

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100053634

Enrollment

Unknown

Registered

2021-11-26

Start date

2021-12-01

Completion date

Unknown

Last updated

2023-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Kidney Injury

Interventions

AKI group:None

Non-AKI group:None

Eligibility

Sex/Gender

All

Age

60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Patients aged >=60 years; 2.ASA I-III patients; 3.Patients with lumbar surgery and joint replacement; 4.Agree to participate in the experiment.

Exclusion criteria

Exclusion criteria: 1.Patients whose preoperative renal function examination indicated that they had reached AKI diagnostic criteria; 2.Patients with severe heart and liver dysfunction or pregnancy and lactation; 3.Patients with kidney disease and operation history; 4.Patients participating in other clinical trials.

Design outcomes

Primary

Measure	Time frame
Incidence of acute kidney injury;	—

Secondary

Measure	Time frame
Neutrophil gelatinase-associated lipid carrier protein concentration;Cys-C concentration;Postoperative urine output;Severity and progress;Incidence and duration of admission to intensive care unit;Death rate;Length of stay and total cost;The occurrence of acute kidney injury;	—

Countries

China

Contacts

Public ContactLiu Jindong

Liujindong1818@163.com+86 13951355136

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026