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Clinical Application of Platelet-rich Plasma Combined with Ozone in Patients with Knee Injury

Clinical Application of Platelet-rich Plasma Combined with Ozone in Patients with Knee Injury: A Single-Center, Prospective, Randomized and Controlled Clinic Trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100053621
Enrollment
Unknown
Registered
2021-11-25
Start date
2021-11-30
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee injury

Interventions

Control group:Intra articular injection of platelet-rich plasma
Experimental group:Intra articular injection of platelet-rich plasma combined with ozone

Sponsors

Department of Pain, Western Theater Command General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Knee injury patients; 2.Physical examination and imaging examination confirmed the diagnosis; 3.A history of sports injuries; 4.Patients without cognitive impairment who volunteered to participate in the study; 5.Aged 18 to 65 years.

Exclusion criteria

Exclusion criteria: 1.Patients with skin diseases around the injection site, skin ulceration around puncture, or obvious swelling and effusion of joints caused by other diseases that cannot be ruled out; 2.Patients with abnormal coagulation function or undergoing anticoagulation therapy; 3.Serious systemic diseases are not under effective control; 4.Have central nervous system disease, mental disease, can not communicate with normal speech; 5.Contraindications of autotransfusion, such as immunosuppression, tumor or other serious diseases; 6.Other circumstances that the investigator considers inappropriate to participate in the study or cannot cooperate with the study for any reason.

Design outcomes

Primary

MeasureTime frame
Koos knee function scale;Imaging changes;

Secondary

MeasureTime frame
General information of patients;Vital signs during treatment;Adverse reactions;Treatment satisfaction score;Treatment expense;Anxiety Self-rating Scale;Health index scale;

Countries

China

Contacts

Public ContactWu Wei

Western Theater Command General Hospital

wuweizj@163.com+86 13008107300

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026