Allergic rhinitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Should meet the diagnostic criteria of allergic rhinitis and be classified as persistent moderate to severe; 2.Aged 2 to 12 years, no gender limitation; 3.The child did not take or receive drugs or treatments that have an impact on the disease during the observation and treatment period; 4.The child has good compliance and the guardian is willing to cooperate with the treatment; 5.Patients who voluntarily participate and sign informed consent.
Exclusion criteria
Exclusion criteria: 1.Allergic to the drugs or tools involved in this experimental protocol; 2.Half a month before treatment, he had taken glucocorticoids, antihistamines, immunosuppressants, etc.; 3.Children with tuberculosis, bronchiectasis, and acute asthma; 4.Children with infectious diseases; 5.With acute attack of bronchial asthma, severe allergic conjunctivitis, chronic rhinosinusitis, upper airway cough syndrome, secretory otitis media, obstructive sleep apnea hypopnea syndrome (OSAHS) caused by adenoid hypertrophy or tonsil enlargement; 6.Obvious physiological and anatomical abnormalities of the nose. Note: patients with any of the above conditions can be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual analog scale for nasal major symptoms;Naso-ocular conjunctiva related quality of life questionnaire;Visual simulation scale of nasal concomitant symptoms;Evaluation table of main clinical symptoms and signs;Untargeted metabolomics of urine and nasal anterior turbinate secretions; | — |
Countries
China