neuromuscular disease
Conditions
Interventions
TOFr>0.9 group:TOFr>0.9 before tracheal extubation
clinical assessment group:Before extubation, the patient was awake, looked up for 5 seconds, had a breathing rate of at least 8 times/min, and a tidal volume of at least 5ml/kg
Sponsors
Eastern Theater General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Sign the written informed consent; 2. Aged 18-65 years; 3. Plan endotracheal intubation; 4. Plan to use muscle relaxants.
Exclusion criteria
Exclusion criteria: 1. Those who are judged by an anesthesiologist to be unsuitable to participate in this trial; 2. The general condition is poor, or there is serious infection, respiratory insufficiency, etc., and cannot take the initiative to cooperate; 3. Have a history of allergy to narcotic drugs; 4. Suspected to have a genetic history of malignant hyperthermia; 5. Those with mental illness, hearing impairment, etc. who cannot communicate; 6. Suffering from neuromuscular disease; 7. Those who refuse to participate in the experiment; 8. The muscle relaxation monitor cannot be installed on the arm; 9. Liver and kidney disease or insufficiency before surgery; 10. Suffering from respiratory diseases; 11. Thoracic and brain surgery.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| grip;ability to sit independently; | — |
Primary
| Measure | Time frame |
|---|---|
| forced vital capacity; | — |
Countries
China
Contacts
Public ContactZhou Zhiqiang
Outcome results
None listed