diabetic retinopathy
Conditions
Interventions
Treatment group:Basic treatment + Qihuang Mingmu Recipe
Control group:Basic treatment
Sponsors
Affiliated Hospital of Nanjing University of Traditional Chinese Medicine (Jiangsu Provincial Hospital of Traditional Chinese Medicine)
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Type 2 diabetes mellitus patients with stage I-III diabetic retinopathy confirmed by fundus photography or fundus angiography, aged 18-70 years, no gender limit; 2. Blood glucose < 16.7mmol/L, blood pressure <= 140/90mmHg, BMI <= 30kg/m^2 in recent 3 months; 3. Sign the written informed consent; 4. TCM syndrome differentiation is deficiency of both qi and yin, dampness and blood stasis blocking the collaterals.
Exclusion criteria
Exclusion criteria: 1. Those who have fundus vein occlusion, uveitis, age-related macular degeneration, hypertensive retinopathy and other diseases that may cause macular edema, those who have obvious cataracts that affect visual inspection, and those who have glaucoma that affects mydriasis inspection (If the above diseases have only one eye but not the other side, this criterion does not apply). 2. Serious primary system diseases such as respiratory, circulatory, digestive, urinary, neurological, blood, rheumatism, endocrine system diseases and tumors, AIDS, etc. 3. Acute complications of diabetes (diabetic ketoacidosis, diabetic nonketotic hyperosmolar syndrome, etc.), serious chronic complications (such as diabetic nephropathy with nephrotic syndrome, severe diabetic peripheral neuropathy, diabetic lower extremity arterial occlusion, etc.). 4. Allergic constitution or known to be allergic or intolerable to the drugs used in this study. 5. Pregnancy, breastfeeding, mental illness or other patients who may lead to decreased compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence, progression and remission of diabetic retinopathy;Vision; | — |
Secondary
| Measure | Time frame |
|---|---|
| Retinal thickness in macular area;Serum TGF-ß1 and a-SMA levels; | — |
Countries
China
Contacts
Public ContactYu Xu
Affiliated Hospital of Nanjing University of Traditional Chinese Medicine (Jiangsu Provincial Hospital of Traditional Chinese Medicine)
Outcome results
None listed