None listed
Conditions
Interventions
Group L :0.50% ropivacaine, 15ml paravertebral block
Group LK :0.50% ropivacaine + 0.25mg/kg esketamine, 15ml paraspinal nerve block
Group LMK :0.50% ropivacaine 15ml paravertebral nerve block + 0.25mg/kg esketamine intramuscular bolus injection
Sponsors
The Second Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 65 years; 2. ASA classification I-II; 3. 18.5 < BMI < 28; 4. Patients undergoing elective single-port thoracoscopic partial pulmonary resection (including lobectomy, segmentectomy, and wedge resection); 5. Postoperative extubation patients.
Exclusion criteria
Exclusion criteria: 1. Patients with known coagulation disorders, poorly controlled diabetes, depression or other mental disorders requiring antidepressants, alcohol or recreational drug addiction, or hypersensitivity to study drugs; 2. Before being included in the study, each patient was tested on the ability of visual analogue scale (VAS), patient-controlled analgesia (PCA) pump operation, answering phone calls and comprehension of Neuropathic Pain Syndrome Scale (NPSI), patients who did not meet these criteria were excluded from the study; 3. Those who are informed and unwilling to participate in the experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sufentanil dosage within 48 h after extubation; | — |
Secondary
| Measure | Time frame |
|---|---|
| The time required to press the analgesia pump button for the first time after extubation;Visual analogue scale;Adverse reactions;Patient satisfaction with pain management during hospital stay;Chronic pain;Depression scale score one week after surgery;Esketamine blood levels;Patient's intraoperative opioid dosage;Sedation score; | — |
Countries
China
Contacts
Public ContactZhu Jiang
The Second Affiliated Hospital of Soochow University
Outcome results
None listed