None listed
Conditions
Interventions
Group A:Continue to take ARB before surgery
Group B:Stop taking ARB before operation
Group C:None
Sponsors
Ji'nan Central Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 79 Years
Inclusion criteria
Inclusion criteria: 1. Elderly patients who are scheduled to undergo lumbar spine surgery in prone position under general anesthesia with tracheal intubation. 2. Aged 60-79 years. 3. Hypertensive patients take ARB antihypertensive drugs on time for at least 3 months and have good blood pressure control. 4. The physical status of the American Society of Anesthesiologists ASA grade <= grade III. 5. Patients who clearly understand and voluntarily participate in the study and sign the informed consent form themselves.
Exclusion criteria
Exclusion criteria: 1. Patients with multiple system diseases: heart failure (ejection fraction = B; creatinine >= 200umol/l) and other severe heart, lung, liver and kidney insufficiency. 2. Shock, moderate to severe anemia (Hb = 180 mmhg or diastolic blood pressure >= 100 mm Hg. 5. Have a history of morbid obesity, BMI >= 30kg/m^2. 6. History of hyperthyroidism. 7. A history of cerebrovascular accident and myocardial infarction in the past 6 months. 8. Patients taking reserpine, ß-blockers and ACEI drugs 1 month before surgery. 9. Participated in clinical trials of other drugs in the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Norepinephrine requirement; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure;Heart rate; | — |
Countries
China
Contacts
Public ContactRen Jie
Ji'nan Central Hospital
Outcome results
None listed