artificial abortion
Conditions
Interventions
experimental group:estradiol gel
control group:Estradiol Gel simulant
Sponsors
Peking Union Medical College Hospital, Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Age >= 18 and = 2 times or missed abortion; 4. The verified true gestational age is less than or equal to 10 weeks, and within three days before operation, the ultrasound shows that the fetal sac (average of three diameters) is more than or equal to >= 1.0cm, and the embryo bud is less than or equal to <= 3.0cm; 5. Preoperative examination is normal according to Clinical Diagnosis and Treatment Guidelines and Technical Operation Specifications: Family Planning Volume (2017 Revision); 6. Be able to follow up regularly and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Contraindications to estrogen; 2. There was a history of intrauterine adhesions or intrauterine operation or correction of uterine malformation confirmed by hysteroscopy; 3. Subjects who are required to place intrauterine devices, oral contraceptives and subcutaneous implants after operation; 4. Those with abnormal mental state and cognitive function who can't cooperate with the treatment process; 5. The researcher thinks that the subject has potential risks or any other factors that interfere with the subject.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Endometrial thickness; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic level of uterine spiral artery; | — |
Countries
China
Contacts
Public ContactLiu xinyan
Peking Union Medical College Hospital, Chinese Academy of Medical Sciences
Outcome results
None listed