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Quantitative CMR evaluation of left ventricular myocardial injury in patients with different stages of CKD

Quantitative CMR evaluation of left ventricular myocardial injury in patients with different stages of CKD

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100053561
Enrollment
Unknown
Registered
2021-11-24
Start date
2021-12-01
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic kidney disease (CKD)

Interventions

CKD stage 1-2 patient group:N/A
CKD stage 3-4 patient group:N/A
Group of patients with CKD stage 5 who did not receive hemodialysis:N/A
End-stage renal disease patients undergoing hemodialysis group:N/A
Control group:N/A

Sponsors

Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Inclusion criteria for CKD patients: (1) Clinically proven CKD patients of different stages in the Department of Nephrology of our hospital; (2) Aged 30-80 years; (3) No history of kidney transplantation; (4) No clear history of cardiovascular disease, no obvious clinical symptoms such as chest pain, chest tightness, palpitations or dyspnea; (5) Normal electrocardiogram performance. 2. Inclusion criteria for normal volunteers: (1) Aged 30-80 years; (2) No history of hypertension (systolic blood pressure <140mmHg; diastolic blood pressure <90mmHg), hyperlipidemia and diabetes; (3) No history of cardiovascular disease, no obvious clinical symptoms such as chest pain, chest tightness, palpitations or dyspnea; (4) The electrocardiogram was normal.

Exclusion criteria

Exclusion criteria: 1. LVEF < 50% after CMR treatment; 2. Pregnant patients; 3. Contraindications for CMR examination; 4. CMR examination found that the left ventricular myocardium was significantly hypertrophic, the size of the heart chamber was abnormal, the myocardial movement was abnormal, and the valve was moderately to severe stenosis or insufficiency; 5. CMR image quality is insufficient.

Design outcomes

Primary

MeasureTime frame
T1 mapping value;T2 mapping value;left ventricular ejection fraction;cardiac index;left ventricular global longitudinal strain;left ventricular global circumferential strain;left ventricular global radial strain;B-type natriuretic peptide;

Countries

China

Contacts

Public ContactShi Heshui

Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology

heshuishi@hust.edu.cn+86 13871089008

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 11, 2026