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Influence of umbilical cord blood mononuclear cell intravenous infusion on dopamine metabolism and curative effects in Parkinson's disease —— a single-center, double-arm, prospective randomized clinical trial

Influence of umbilical cord blood mononuclear cell intravenous infusion on dopamine metabolism and curative effects in Parkinson's disease —— a single-center, double-arm, prospective randomized clinical trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100053548
Enrollment
Unknown
Registered
2021-11-24
Start date
2021-12-01
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson's disease (PD)

Interventions

Control group:Traditional drug therapy + saline infusion
Experimental group:Traditional drug therapy + cord blood mononuclear cell intravenous infusion

Sponsors

Yantaishan Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-75 years, no gender limit; 2. Meet the diagnostic criteria for PD of the British Brain Bank; 3. Subjects and their families understand the clinical trial protocol and voluntarily participate in the trial and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Various secondary Parkinson's syndrome, Parkinson's superimposed syndrome and other non-primary PD; 2. Complicated with serious cardiovascular and cerebrovascular diseases or other major diseases of digestion, breathing, blood and other systems; 3. Combined with tumor or past tumor history; 4. Combining with other serious neurological and mental system diseases and unable to cooperate; 5. Patients deemed unsuitable for inclusion by the investigator.

Design outcomes

Primary

MeasureTime frame
Unified Parkinson's Scale Parts II and III Scores;Determination of high vanillic acid content;Parkinson's Non-Motor Symptom Scale Score;Parkinson's Patient Quality of Life Questionnaire (PDQ-39);Pittsburgh Sleep Quality Index;

Countries

China

Contacts

Public ContactKong Min
kk_kmm@sina.com+86 535 6863786

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026