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A randomized controlled clinical study of hyperbaric oxygen in the prevention of acute altitude sickness

A randomized controlled clinical study of hyperbaric oxygen in the prevention of acute altitude sickness

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100053534
Enrollment
Unknown
Registered
2021-11-24
Start date
2022-01-01
Completion date
Unknown
Last updated
2022-10-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute mountain sickness

Interventions

Hyperbaric oxygen preconditioning group 1:hyperbaric oxygen preconditioning
Control group:none
Hyperbaric oxygen preconditioning group 2:hyperbaric oxygen pretreatment pressure: 2.0 ATA

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. Normal healthy population; 2. Aged between 18-50 years; 3. Gender is not limited.

Exclusion criteria

Exclusion criteria: 1. Unstable vital signs; 2. Combined with epilepsy, dementia, Parkinson's disease and other neurological diseases; 3. Complicated with hypertension, diabetes, asthma, chronic obstructive pulmonary disease, thyroid disease, severe liver and kidney insufficiency, and insufficiency of important organs such as heart and lung; 4. Absolute contraindications and relative contraindications of combined hyperbaric oxygen therapy: 5. Combined with schizophrenia, bipolar affective disorder, panic attack, obsessive-compulsive disorder, depression or claustrophobia; 6. Combined pregnancy; 7. Previous high altitude sickness such as severe altitude maladaptation, high altitude cerebral edema, and high altitude pulmonary edema; 8. Patients or their families refuse to sign the informed consent.

Design outcomes

Primary

MeasureTime frame
Lake Louise Score for Acute Mountain Sickness;Pulse;Blood pressure;Blood oxygen saturation;

Countries

China

Contacts

Public ContactHuang Cheng

West China Hospital of Sichuan University

chenghuang_scu@163.com+86 18980603143

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026