Cerebral vascular disease
Conditions
Interventions
Control group:Pseudo hyperbaric oxygen stimulation
Sponsors
Ningbo Kangning Hospital
Eligibility
Sex/Gender
All
Age
30 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Those who meet the definition of stroke by the World Health Organization (WTO); 2. Diagnosed with cerebral hemorrhage, cerebral infarction or cerebral small vessel disease by brain CT or MRI and other imaging data, aged 30-80 years; 3. Meet the DSM-5 symptom criteria for depression; 4. The total score of 17 items of HAMD scale is more than 7 points; 5. Clear consciousness, stable vital signs, no aphasia and other comprehension and expression barriers and serious intellectual impairment; 6. Inform the family members of various risks that the patient may have during the research and treatment process. The family members are aware of the above risks, agree to be enrolled and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Severe heart, lung, kidney, epilepsy, glaucoma, substance dependence and other diseases; 2. Those with contraindications to hyperbaric oxygen; 3. Termination of treatment due to changes in condition.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hamilton Depression Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment;Mini-mental State Examination;Hachinski Ischemic Scale;Barthel Index Scale;Pittsburgh Sleep Quality Index Scale;Neuropsychiatric Inventory, NPI;Electroencephalophysiological indicators;Functional near-infrared spectroscopy;Neurotransmitter power;Polysomnography; | — |
Countries
China
Contacts
Public ContactZhao Yuanzhi
Ningbo Kangning Hospital
Outcome results
None listed