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Clinical study of lenalidomide maintenance after chemotherapy for intermediate and high-risk B-cell lymphoma

Clinical study of lenalidomide maintenance after chemotherapy for intermediate and high-risk B-cell lymphoma

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100053520
Enrollment
Unknown
Registered
2021-11-24
Start date
2020-07-01
Completion date
Unknown
Last updated
2022-10-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

B-cell lymphoma

Interventions

Treatment group:Oral maintenance therapy with lenalidomide

Sponsors

The Second Hospital of Dalian Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Aged >=18 years and = 1x10^9/L, platelet count (PLT) >= 75x10^9/L, unless due to bone marrow invasion; 5. Biochemical indicators before enrollment must be within the following ranges: (1) Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) = 40ml/min; 6. The LVEF value determined by echocardiography is within the normal range of the institution; 7. The researcher judges that the life expectancy is >= 3 months.

Exclusion criteria

Exclusion criteria: 1. The presence of central nervous system lymphoma. 2. Associated with uncontrolled cardiovascular and cerebrovascular diseases, coagulation disorders, connective tissue diseases, serious infectious diseases and other diseases. 3. Pregnant or lactating patients. 4. The presence of human immunodeficiency virus (HIV) virus infection. 5. There is a history of other malignant tumors in the past, unless the disease has been cured for 5 years or more. Except for the following tumors that have been cured: (1) Skin basal cell carcinoma, skin squamous cell carcinoma and related localized non-melanoma skin cancer; (2) Cervical carcinoma in situ.

Design outcomes

Primary

MeasureTime frame
Overall Response Rate ;Progress Free Survival;

Secondary

MeasureTime frame
Complete Response;Overall Survival;Adverse Event Rate;

Countries

China

Contacts

Public ContactWang Xiaobo

The Second Affiliated Hospital of Dalian Medical University

wangxb1007@outlook.com+86 17709871007

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026