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Effects of combined dexamethasone and ropivacaine in continuous serratus anterior plane block on postoperative pain after thoracoscopy

Effects of combined dexamethasone and ropivacaine in continuous serratus anterior plane block on postoperative pain after thoracoscopy

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100053518
Enrollment
Unknown
Registered
2021-11-24
Start date
2021-11-24
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Group RD:Ropivacaine + Dexamethasone

Sponsors

The First Affiliated Hospital of University of Science and Technology of China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients with elective thoracoscopic lobectomy; 2. Gender is not limited, aged 18 to 70 years; 3. BMI is in the range of 18.5-30kg/m^2, and ASA is graded I-III; 4. Voluntarily participate in this research and sign the preoperative informed consent; 5. The patient has the ability to accurately complete the pain assessment.

Exclusion criteria

Exclusion criteria: 1. History of previous thoracic surgery; 2. Coagulation disorders, etc.; 3. Liver and kidney insufficiency, cardiac insufficiency (New York Heart Association grades III-IV), pulmonary function damage (forced expiratory volume within 1s <50% predicted value); 4. Allergy to local anesthetics or opioids; 5. Preoperative history of chronic pain or continuous analgesia; 6. Whole body or puncture site infection; 7. Peripheral nervous system disease or nerve damage in the SAPB area; 8. Diabetes; 9. Other conditions that the investigator believes that the patient does not meet the conditions of this study.

Design outcomes

Primary

MeasureTime frame
The sum of pressing numbers within 48h after surgery;The time to first patients-controlled bolus;

Secondary

MeasureTime frame
The incidence of additional analgesia;The occurrence of wound infection;The occurrence of nausea and vomiting;Visual analogue scale;

Countries

China

Contacts

Public ContactWang Di
di.wang@ustc.edu.cn+86 13515604532

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026