Skip to content

Prospective randomized controlled study of individualized nutritional intervention to improve maternal and infant outcomes in pregnant women at high risk of pregnancy hypertension

Prospective randomized controlled study of individualized nutritional intervention to improve maternal and infant outcomes in pregnant women at high risk of pregnancy hypertension

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100053502
Enrollment
Unknown
Registered
2021-11-23
Start date
2021-12-01
Completion date
Unknown
Last updated
2022-10-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypertensive disorder of pregnancy

Interventions

Experimental group:Individualized nutritional monitoring and guidance during pregnancy
Control group:Routine group nutrition education

Sponsors

Army Specialized Medical Center
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Pregnant women with singleton pregnancy 6-13+6 weeks in our hospital for prenatal examination; 2. Use the Mp pregnancy-induced hypertension syndrome monitoring system to screen out the high-risk of pregnancy-induced hypertension during the first prenatal visit, or the low-risk but one of the following high-risk factors: (1) Aged >= 40 years; (2) History of preeclampsia, positive antiphospholipid antibody, hypertension (no organic damage), chronic nephritis (normal renal function in this pregnancy), diabetes or hereditary thrombosis; (3) BMI >= 35kg/m^2 at the first obstetric examination; (4) Family history of preeclampsia (mother or sister); (5) First pregnancy, pregnancy interval >= 10 years, and systolic blood pressure >= 130 mmHg or diastolic blood pressure >= 80 mmHg in the first trimester.

Exclusion criteria

Exclusion criteria: 1. There is a history of premature birth and a history of stillbirth; 2. A history of fetal growth restriction and low birth weight; 3. A history of postpartum hemorrhage and placental abruption; 4. Have a history of serious cardiovascular and cerebrovascular, endocrine and blood system diseases.

Design outcomes

Primary

MeasureTime frame
Incidence of hypertensive disorder of pregnancy;

Secondary

MeasureTime frame
Pregnant women gain weight;Preterm birth;Blood routine;Liver function;Renal function;Blood lipids;Whether there is gestational diabetes in the middle and late stages of pregnancy;Neonatal weight;Apgar score;The influence of dietary structure (FFQ questionnaire) on hypertensive disorder of pregnancy in Chongqing;

Countries

China

Contacts

Public ContactZheng Xiuhui

Army Specialized Medical Center

lph1972@163.com+86 15823495993

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026