Infertility
Conditions
Interventions
Modified antagonist protocol (study group):If at least one follicle measuring >=13 mm, or serum LH >=10 IU/l, or serum estradiol level=600pg/ml, daily subcutaneous injections of the GnRH antagonist (C
Conventional antagonist protocol (control group):Conventional antagonist protocol (control group): If at least one follicle measuring >= 13 mm, or serum LH >=10 IU/l, or serum estradiol >= 600pg/ml, d
Sponsors
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
Female
Age
21 Years to 39 Years
Inclusion criteria
Inclusion criteria: 1. Aged 1.1 ng/ml; 3. Basal antral follicle count (AFC) > 5.
Exclusion criteria
Exclusion criteria: 1. Patients with polycystic ovary syndrome and polycystic ovary; 2. Hydrosalpinx, uterine abnormalities, adenomyosis, hyperprolactinemia, chromosomal aberrations, recurrent spontaneous abortion; 3. Congenital adrenal hyperplasia, thyroid disease; 4. Patients using oral contraceptive(OC), or receiving sperm from testicular sperm extraction (TESE), testicular sperm aspiration (TESA), or micro TESE.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Live birth rates per fresh cycle; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical pregnancy rate;Total dose of Gn used and Gn duration;E2 and P concentrations on hCG day;Number of oocytes retrieved;Number of MII oocytes;Implantation rate;Ongoing pregnancy rate;2PN rate;Good-quality embryo rate;Blastocyst formation rate;Early pregnancy loss rate/Abortion rate;Number of embryos obtained;>= 14mm follicle count;Cycle cancellation rate;Live birth rate per frozen embryo transfer cycle;Cumulative live birth rate; | — |
Countries
China
Contacts
Public ContactXu Bei
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed