Strabismus
Conditions
Interventions
Ciprofol group:Intravenous injection of Ciprofol 0.3mg/kg
Propofol group:Intravenous injection of Propofol 1.5mg/kg
Sponsors
the Affiliated Hospital of Yunnan University
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. 18-45 years old, gender is not limited; 2. American Anesthesiologist Classification (ASA) I-II; 3. Patients who need MAC for elective strabismus surgery; 4. Body mass index (BMI) >=18 and =10 and =95% when breathing air; systolic blood pressure (SBP) >=90mmHg and =60mmHg and =55 and <=100 beats/min; 6. Be able to understand the research process and methods, and voluntarily participate in this research.
Exclusion criteria
Exclusion criteria: 1. Those with contraindications to intravenous general anesthesia or those who have had a history of anesthesia accident in the past; 2. Known or suspected to be allergic or contraindicated to propofol injection, cyclopofol injection and other excipients; 3. Combined with craniocerebral loss, intracranial hypertension, stroke, unstable angina, myocardial infarction; 4. Respiratory insufficiency, obstructive pulmonary disease, having a difficult airway, or being judged to have difficulty in endotracheal intubation (modified Markov score grade III or IV) 5. Severe liver dysfunction or severe renal insufficiency; 6. History of alcoholism or drug dependence; 7. Abuse or long-term use of narcotic, sedative, and analgesic drugs; 8. Those who have a history of mental illness in the past; 9. Those who have participated in any drug clinical trials within 1 month before screening; 10. Pregnant and lactating women; fertile women or men who are unwilling to use contraception throughout the trial period; subjects (including male subjects) who have a pregnancy plan within 1 month after the trial; 11. Subjects who are considered by the investigator to have any other factors that are not suitable for participating in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rate of anesthesia induction; | — |
Countries
China
Contacts
Public ContactSu Guoning
the Affiliated Hospital of Yunnan University
Outcome results
None listed