Femoral head necrosis
Conditions
Interventions
Control Group:Femoral head core decompression
Test group:Core decompression combined with allogeneic bone grafting
Sponsors
Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-50 years; 2. Patients with femoral head necrosis caused by hormone therapy; 3. Stage II patients according to ARCO stage of femoral head necrosis; 4. Patients who understand the purpose of the trial, voluntarily sign the informed consent form, and agree to complete the entire research process in accordance with the requirements of the protocol.
Exclusion criteria
Exclusion criteria: 1. Patients who have undergone surgical treatment of the femoral head; 2. Accompanied by acute or severe infection; 3. Patients with severe cardiovascular and cerebrovascular diseases, diabetes, coagulation disorders, mental and nervous system diseases, etc., with a history of severe osteoporosis, calcium and phosphorus metabolism disorders, drug abuse, etc.; 4. Patients with acute exacerbation of chronic diseases; 5. Patients with malignant disease and the survival period is less than 24 months; 6. Liver function exceeding 1.5 times the normal range; 7. Those whose creatinine level exceeds 1.5 times the normal range; 8. Women who are planning to become pregnant; 9. Pregnant and lactating women; 10. Patients with poor compliance and unable to follow up on time; patients who participated in other clinical trials during the same period but did not reach the end point; other patients who were deemed unsuitable by the investigator to participate in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hip Harris Score;Association Research Circulation Osseous; | — |
Secondary
| Measure | Time frame |
|---|---|
| visual analogue scale;Surgery related complications;Length of stay;Operation time;Perioperative bleeding; | — |
Countries
China
Contacts
Public ContactXu Jie
Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University
Outcome results
None listed