Canceled by the investigator. Effect of anthocyanin supplementation on ß cell function and insulin sensitivity in subjects with isolated impaired glucose tolerance: a double-blind, randomized, placebo-controlled trial

Effect of anthocyanin supplementation on ß cell function and insulin sensitivity in subjects with isolated impaired glucose tolerance: a double-blind, randomized, placebo-controlled trial

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100053418

Enrollment

Unknown

Registered

2021-11-20

Start date

2021-11-27

Completion date

Unknown

Last updated

2023-12-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Isolated impaired glucose tolerance

Interventions

Intervention group:anthocyanin capsules

Control Group:Placebo

Eligibility

Sex/Gender

All

Age

30 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Male or female aged 30 to 60 years; 2. After fasting blood glucose =7.8mmol/L and <11.1mmol/L; 3. The weight change in the past 3 months is less than 2kg; 4. BMI <= 32 kg/m^2; 5. Ability and willingness to participate in trials.

Exclusion criteria

Exclusion criteria: 1. Suffering from one of the following diseases: cardiovascular disease; diabetes; gastrointestinal disease (except mild chronic superficial gastritis); cancer; thyroid disease; liver disease (except mild fatty liver); other serious acute and chronic diseases ; 2. Impaired liver function (defined as glutamate aminotransferase (ALT) 3 times the upper reference limit of normal); 3. Impaired renal function (defined as serum creatinine > 110 umol/L); 4. Pregnant or breastfeeding women; 5. Women planning to become pregnant or not taking adequate contraceptive measures; 6. Taking hypoglycemic drugs or hormone drugs in the past 6 months; 7. Taking dietary supplements in the past 2 months; 8. More than 2 hours of moderate-intensity exercise or more than 1 hour of high-intensity exercise per week; 9. The daily intake of alcohol exceeds 25g for men or 15g for women.

Design outcomes

Primary

Measure	Time frame
Disposition index;	—

Secondary

Measure	Time frame
IGI(30);IGI(60);AUC of plasma glucose;AUC of plasma insulin;AUC of plasma C-peptide;Matsuda index;first phase stumvoll;second phase stumvoll;HOMA-ß;stumvoll insulin sensitivity index;Gutt ISI;HOMA-IR;retinol binding protein 4;	—

Countries

China

Contacts

Public ContactZhao Lina

Sun Yat-Sen University

zhaoln5@mail.sysu.edu.cn+86 13326422823

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026