Distant metastasis of breast cancer
Conditions
Interventions
case series:Nil
Sponsors
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-70 years, and the pathological diagnosis can be obtained by operation or biopsy; 2. Clinical diagnosis or diagnosis of breast cancer; 3. Biopsy has confirmed metastasis of distant organs and tissues. It is proposed or confirmed to be HER2 receptor positive through IHC analysis, and Herceptin treatment is decided; 4. Informed consent in writing signed by the subject or his legal guardian and caregiver; 5. If necessary, the subject can be accompanied by nursing staff; 6. Before any evaluation, the subject or his legal representative understands and signs the written informed consent; 7. Female subjects must have medical records to prove that they have passed surgical sterilization (such as hysterectomy, bilateral ovariectomy or tubal ligation) or menopause for more than one year; If you still have the ability to conceive, you must take isolated contraceptive measures at the stage of this study; 8. Willing and able to cooperate with all projects of this study.
Exclusion criteria
Exclusion criteria: 1. Suffering from gastrointestinal, cardiovascular, renal, blood system, endocrine, respiratory system, immunodeficiency or other serious diseases; 2. In the past year, due to other clinical medical or scientific research needs, received ionizing radiation outside the scope of this experiment, so that the annual radiation exposure dose exceeded 50 mSv; 3. History of drug or alcohol abuse; 4. Pregnant or lactating women. 5. Poor venous conditions, unable to tolerate repeated venipuncture; 6. Received (unclear effect or safety) experimental drug or device treatment within 1 month; 7. May be allergic to the components of 99mTc-HPArk2 injection; 8. Have any conditions that the host of this study believes that any link related to this experiment may cause harm or have potential harm.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Correlation between 99mTc hpark2 uptake and Herceptin efficacy; | — |
Countries
China
Contacts
Public ContactSong Erwei
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Outcome results
None listed